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11 An ongoing phase I/II clinical trial (NCT 04585750) has assessed the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of PC14586 administration in patients with advanced solid tumors harboring the p53 Y220C mutation

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Importantly, SGLT2 is targeted by a class of highly efficacious drugs known as gliflozins, which reduce renal glucose reabsorption, thereby aiding in the management of glycemia and improving cardiovascular and metabolic health (Teo et al., 2021